February 23, 2018

Blood Test May Lead to Earlier, More Accurate Autism Diagnosis

download (2)Two metabolic biomarkers accurately predict autistic spectrum disorders (ASDs) in children, new research shows.

A multivariate statistical analysis conducted by investigators at Rensselaer Polytechnic Institute in Troy, New York, “provides unprecedented quantitative classification results” that accurately identify children with ASD and neurotypical children.

For the study, investigator Juergen Hahn, PhD, professor and head, Department of Biomedical Engineering, Rensselaer Polytechnic Institute, and colleagues measured blood concentrations of two metabolites — the folate-dependent one-carbon mechanism (FOCM) and transulfuration (TS) pathways — in 83 children with ASD, 47 siblings, and 76 age-matched neurotypical peers. The children ranged in age from 3 to 10 years.  Read more…